13P Dosimetric comparisons of brachytherapy applicators used in carcinoma cervix and their utility in toxicity prediction

نویسندگان

چکیده

BackgroundBrachytherapy is an important component in management of cervical cancer, enabling dose escalation with reasonable limitation toxicity. However, some patients, there inadvertent increase OAR (Organs at Risk) doses. In our study, we analyse the dosimetric differences between two commonly used ICBT (Intracavitary Brachytherapy) applicators hospital.MethodsWe performed a retrospective analysis intracavitary brachytherapy (ICBT) plans using clinical records 109 cervix cancer patients from Aug-2020 to Aug-2021. Patients who completed course same were chosen. 3 month follow up and symptom data was acquired records. The mean doses per patient compared FSD (Fletcher Suit Delclos) Ring-Tandem applicator ring cap.ResultsRing Tandem 67 while Fletcher Delclos 42 patients. bladder D2cc (Highest irradiated 2cc area), rectum 79.2% vs 50.4% 63.2%. (σ = 19.4) (Posterior Inferior Border Pubic Symphysis) PIBS +2 146% 218.5% 49% 83.6%. At time months up, incidence Grade 2 dysuria (0.5% v 19.5%, p<0.05) Analysing anatomical parameters, AP pelvic diameter correlated negatively average OARs. volume positively (ρ, correlation coefficient 0.44). (ρ 0.01) 0.15) level flange also D2cc.ConclusionsIt can be inferred study that tandem has comparably favorable profile it should evaluated further, view decrease toxicities improve free quality life. looked into further as marker vaginal toxicity urethral toxicity, delivery optimised accordingly.Legal entity responsible for studyThe authors.FundingHas not received any funding.DisclosureAll authors have declared no conflicts interest. hospital. Brachytherapy MethodsWe cap. We ResultsRing D2cc. Ring ConclusionsIt accordingly. It

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2022

ISSN: ['0923-7534', '1569-8041']

DOI: https://doi.org/10.1016/j.annonc.2022.04.031